There are many good bacteria! There is only 1 BULARDI®

Not all probiotics are the same.
What is the difference?
Probiotics are living microorganisms that, in adequate amounts, exert beneficial effects on human health. However, there are differences between probiotics, and thus probiotic products.

- Especially the aTECH packaging provides additional protection to probiotic cells, increasing stability, i.e., sustainability of probiotic strains, which enhances product efficacy.
- On product labeling, it is extremely important that the number of probiotic cells is declared at the end of the shelf life, rather than at the time of packaging.
- Probiotics are LIVE microorganisms whose count decreases over time, reducing the effectiveness of the product. Therefore, when choosing a quality product, it is important to ensure that the label contains the number of probiotic cultures until the expiration date.
- Clinically proven for all forms of diarrhea4
- Quality GUARANTEED by the Probiotic Excellence Center

10 TIMES LARGER
Saccharomyces boulardii has a surface area 10 times larger than probiotic bacteria. This enhances the binding of a larger number of pathogens and accelerates their elimination.

SIMULTANEOUSLY WITH ANTIBIOTICS
Safe with all antibiotics, as there is no possibility of genetic material transfer between bacteria and fungi.

100 YEARS IN 90 COUNTRIES
The unique probiotic yeast contributes to faster diarrhea cessation, normalization of bowel function, and microbiota recolonization.

ACCORDING TO WGO AND ESPGHAN
First recommendation:
WGO and ESPGHAN
for children and adults with diarrhea.4
Probiotic with antibiotic?
Take BULARDI®
-
Dominant
One Bulardi cell is 10x larger than the cell of some other probiotics Special
Faster, better, and safer removal of toxins from the intestinesDifferent
Because it can be used simultaneously with antibioticsInnovative
Special aTECH technology guarantees stability and quality
There are many probiotics, there is only one Bulardi
QUALITY GUARANTEED BY THE PROBIOTIC EXCELLENCE CENTER®!
The Probiotic Excellence Center® by Abela Pharm is a scientific research center dedicated to the development of probiotic strains, researching optimal combinations of probiotic strains for use in specific therapeutic areas, developing new generations of probiotic products, and technological innovations.
Leading scientific experts – doctors of science from various fields, working according to European standards and utilizing state-of-the-art equipment and technology, make this unique center one of the most qualified producers of probiotic products in Europe.
They are produced in accordance with European and international manufacturing and quality standards: EU GMP, GMP, GDP, HACCP, ISO 9001:2015, ISO 22000:2018, ISO 14001:2015, ISO 13485:2017.

CLINICALLY PROVEN
EFFECTIVELY CONTRIBUTES TO REDUCING
THE INCIDENCE OF ANTIBIOTIC-ASSOCIATED DIARRHEA1

CONTRIBUTES TO REDUCING UNDESIRABLE
THE EFFECT OF H. PYLORI ERADICATION3

EFFECTIVELY CONTRIBUTES TO REDUCING
THE RISK OF C. DIFFICILE-ASSOCIATED DIARRHEA2

ADVANTAGES OF aTECH PACKAGING
INNOVATION – THE KEY
TO PROGRESS AND DEVELOPMENT
VISION towards which all activities of the Probiotic Excellence Center® are directed is to be the leading center for the production of probiotic products in Europe.
Accordingly, we are guided by QUALITY as the main value we want to provide to users of our probiotic products, and we pay great attention to INNOVATIONS focused on the production process, packaging technology, and preservation of the physiology and metabolism of probiotic strains.
Innovation that we are extremely proud of and that sets us apart from other probiotic manufacturers is the development of the unique aTECH technology, which provides additional protection for blister-encapsulated probiotics with a three-layer bag filled with inert gas. In this way, all probiotic preparations coming from the Probiotic Excellence Center® guarantee stability and preservation of the number of probiotic cells in the preparation until the EXPIRATION DATE.




There are many probiotics.
There is only one BULARDI®!
Reference:
1. Prophylactic Saccharomyces boulardii in the prevention of ADD, A prospective study.Can et al. Med Sci Monit. 2016; 12(4):
2. Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease, Am J Gastroenterol, 2006 Apr;101(4):812-22
3. Saccharomyces boulardii as an adjuvant therapy for Helicobacter pylori eradication: A systematic review and meta-analysis with trial sequential analysis, Ben-Gang Zhou, Ling-Xiao Chen, Bo Li, Lin-Yan Wan, Yao-Wei Ai, PubMed, 2019 Oct;24(5):e12651.
4. WGO World Gastroenterology Organisation Practice Guideline 2023.
5. McFarlan L. et al. Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World J Gastroenterol 2010; 16(18): 2202-2222.
6. Floch M. et al. Recommendations for Probiotic Use—2015 Update. Proceedings and Consensus Opinion. J Clin Gastroenterol 2015; 49:569-573.
7. McFarland LV. Meta-analysis of probiotics for the prevention of traveler’s diarrhea. Travel Med InfectDis 2007; 5: 97-105.
8. Wong A. et al. Detection of antibiotic resistance in probiotics of dietary supplements. Nutrition Journal 2015; 14:95.
9. Panic N. et al. Prophylactic use of Saccharomyces boulardii probiotics in preventing antibiotic-associated diarrhea: a single center hospital-based case-control study in Serbia. Epidem Biostat and Public Health 2015; 12(4). DOI: 10.2427/11607